Guanfacine Hydrochloride Guanfacine HCl CAS 29110-48-3 API USP Standard High Purity
Manufacturer with High Purity and Stable Quality
Chemical Name: Guanfacine Hydrochloride
Synonyms: Guanfacine HCl
CAS: 29110-48-3
Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist. Antihypertensive
API High Quality, Commercial Production
Chemical Name | Guanfacine Hydrochloride |
Synonyms | Guanfacine HCl |
CAS Number | 29110-48-3 |
CAT Number | RF-API40 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C9H10Cl3N3O |
Molecular Weight | 282.55 |
Melting Point | 211.0~215.0℃ |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White to Off-White Crystalline Powder |
Identification | Infrared Absorption; HPLC |
Loss on Drying | ≤0.50% |
Residue on Ignition | ≤0.10% |
Heavy Metals | ≤20ppm |
Assay | 98.0%~102.0% (HPLC on dried basis) |
Chromatographic Purity | ≥99.0% |
Test Standard | USP Standard |
Usage | Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
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Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Guanfacine Hydrochloride (CAS: 29110-48-3) with high quality.
Guanfacine hydrochloride centrally acting a-adrenoceptor agonist. Antihypertensive. Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors. Guanfacine lowers both systolic and diastolic blood pressure by activating the central nervous system α2A norepinephrine autoreceptors, which results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone. The therapeutic applications for guanfacine are similar to those of the other centrally acting α2-adrenergic agonists and methyldopa. It has been effective as monotherapy in the treatment of patients with mild to moderate hypertension.
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